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本文研究婴儿及小儿脑膜炎患者脑脊液中和血清中IL-6的活性检测与其他炎症及后果的相关性。作者检测42例刚入院的年龄在1个月～15周岁(平均年龄为2.5周岁)的细菌性脑膜炎患儿脑脊液及血清中IL-6的活性。其中36例未经治疗的患儿脑脊液中有30例检测到IL-6(IL-6活性者高于50U/ml)。所检测到的IL-6活性为36000U/ml(范围151～156000u/ml),而经治疗后的23例患儿脑脊液中,仅1例检测到IL-6的活性。患
This article investigates the correlation between IL-6 activity in cerebrospinal fluid and serum in infants and children with other meningitis and other consequences of inflammation and consequences. The authors tested the activity of IL-6 in cerebrospinal fluid and serum from 42 patients with bacterial meningitis who were admitted to hospital from 1 month to 15 years of age (mean age 2.5 years). In 36 of 36 untreated children, CSF-IL-6 (IL-6 activity above 50 U / ml) was detected in 30 of the children. The IL-6 activity detected was 36,000 U / ml (range 151-156,000 u / ml), whereas IL-6 activity was detected in only 1 of 23 treated children with cerebrospinal fluid. Suffering