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随着药剂学与其他学科理论和先进技术的发展,许多新型给药系统在兽医临床的应用有逐步增加的趋势。在众多给药系统中,透皮贴剂通过皮肤敷贴给药后在体内长时间保持稳定有效的血药浓度和治疗作用,为一些慢性疾病和局部镇痛的治疗及预防提供了一种使用简单方便和安全有效的给药方式。国内外已积极开发兽药透皮制剂,并在试验应用中取得了满意效果。文章结合目前国内外兽药透皮贴剂的研究,系统阐述了透皮贴剂的发展现状与特点、影响透皮的因素及该剂型在兽药临床中的使用评价。
With the development of pharmaceutics and other academic theories and advanced technologies, many new drug delivery systems have shown a gradual increase in the clinical application of veterinary medicine. In many drug delivery systems, the transdermal patch maintains a stable and effective plasma concentration and therapeutic effect in the body for a long time after it is applied through the skin and provides a kind of use for the treatment and prevention of some chronic diseases and local analgesia Simple and convenient and safe and effective mode of administration. At home and abroad have actively developed veterinary drug transdermal preparation, and obtained satisfactory results in the test application. Combined with the current research on transdermal patches of veterinary drugs both at home and abroad, the article systematically expounds the development status and characteristics of transdermal patches, the factors that affect transdermal delivery and the evaluation of the application of the transdermal patch in veterinary drugs.