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目的:探究促甲状腺激素抑制疗法在分化型甲状腺癌治疗中的应用效果。方法:根据术后处理方法的不同将28例行甲状腺切除术DTC患者分为研究组(15例)和对照组(13例),分别采用TSH抑制治疗和甲状腺素替代治疗,比较两组术后无复发、无转移情况。结果:研究组术后3年无复发和转移率(93.3%)高于对照组(84.6%),比较差异显著(P<0.05)。结论:TSH抑制疗法在DTC手术治疗中效果显著,有助于控制或延缓术后DTC复发或转移,具有较高的临床应用价值。
Objective: To investigate the effect of thyrotropin-inhibiting therapy in the treatment of differentiated thyroid cancer. Methods: Twenty-eight patients undergoing thyroidectomy with DTC were divided into study group (n = 15) and control group (n = 13) according to the different postoperative management methods. TSH suppression therapy and thyroid hormone replacement therapy were used respectively. No recurrence, no transfer. Results: The recurrence rate and metastasis rate of the study group after 3 years (93.3%) were significantly higher than those of the control group (84.6%) (P <0.05). CONCLUSIONS: TSH inhibition is effective in the treatment of DTC, which is helpful to control or delay the recurrence or metastasis of DTC after operation. It has high clinical value.