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Barrett食管(Barrett’s Esophagus,BE)是指食管下段复层鳞状上皮被单层柱状上皮所替代的一种病理现象,可伴肠化或无肠化,伴有特殊肠上皮化生者是属于食管腺癌的癌前病变[1]。有研究发现,约80.0%的食管腺癌来源于BE[2],其中伴有高度不典型增生的BE(HGD-BE)发展为食管腺癌的风险性更高,一项荟萃分析[3]报道每年约有6.0%的HGDBE患者发展为食管腺癌,且HGD-BE患者未来5
Barrett’s Esophagus (BE) is a pathological phenomenon in which the lower esophageal squamous epithelium is replaced by a single columnar epithelium, which may or may not be associated with intestinal metaplasia. Patients with special intestinal metaplasia belong to the esophagus Adenocarcinoma precancerous lesions [1]. Some studies have found that about 80.0% of esophageal adenocarcinomas originate from BE [2]. BE (HGD-BE) with high-grade dysplasia has a higher risk of developing esophageal adenocarcinoma. A meta-analysis [3] It is reported that about 6.0% of HGDBE patients develop esophageal adenocarcinoma each year, and the future of HGD-BE patients 5