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观察52例Binswanger病（BD）患者的血液流变学指标，并与体检健康者（对照组）比较，结果：BD组的MCV、MCH、MCHC及高切交率全血粘度均显著高于对照组（P＜0．05～0．01），红细胞变形指数显著高于对照组（P＜0．01）。提示BD患者的红细胞发生了生理性衰老和程度不同的病理性变化，此种质的变化使红细胞内粘度增加，红细胞变形能力下降，刚性增强，导致大脑白质血流失去连续性，造成脑组织缺血、缺氧等一系列病理改变，揭示血液流变学异常可能参与了BD的发病机制。
The hemorrheological indexes of 52 Binswanger’s disease (BD) patients were observed and compared with those of the healthy controls (control group). The results showed that the MCV, MCH, MCHC and high shear rate whole blood viscosity in BD group were significantly higher than those in control group Group (P <0.05 ~ 0.01), erythrocyte deformation index was significantly higher than the control group (P <0.01). Prompted BD patients with physiological aging of erythrocytes and varying degrees of pathological changes, such qualitative changes in intra-erythrocyte viscosity, decreased erythrocyte deformability, increased rigidity, resulting in loss of continuity of the white blood flow of the brain, resulting in brain tissue missing Blood, hypoxia and a series of pathological changes revealed that abnormal blood rheology may be involved in the pathogenesis of BD.