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目的了解2013年山东省成年居民血脂异常状况和主要危险因素,为血脂异常的防治提供依据。方法于2013年9-11月采用多阶段分层整群随机抽样方法,选取山东省19个慢性病危险因素监测点的10 686名18岁以上成年居民为调查对象,进行问卷调查并抽取静脉血,检测总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和甘油三酯(TG)水平。数据均经过复杂加权进行调整,用SAS 9.3软件进行相关危险因素的logistic回归分析。结果调查对象血脂异常率为31.6%。多因素logistic回归分析结果显示,日吸烟量20支及以上(OR=1.293,95%CI:1.290~1.295)、3级饮酒(OR=1.103,95%CI:1.101~1.106)、低水平身体活动(OR=1.186,95%CI:1.185~1.188)、高血压(OR=1.548,95%CI:1.546~1.550)、高血糖(OR=1.589,95%CI:1.587~1.591)、中心性肥胖(OR=1.774,95%CI:1.772~1.777)、肥胖(OR=2.565,95%CI:2.560~2.569)等均是血脂异常的危险因素,差异均有统计学意义(P<0.01)。其中肥胖、中心性肥胖和高血糖是最为重要的危险因素。结论山东省成年居民血脂异常率较高,应及早针对具有血脂异常主要危险因素的高危人群,通过改变饮食和生活习惯降低血脂异常患病率。
Objective To understand the prevalence of dyslipidemia and risk factors of adult residents in Shandong Province in 2013 and provide basis for the prevention and treatment of dyslipidemia. Methods From September to November in 2013, a multistage stratified cluster random sampling method was used to select 10 686 adult residents over the age of 18 from 19 chronic disease risk monitoring sites in Shandong Province as subjects, The levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) were measured. Data were adjusted with complex weights and logistic regression analysis of relevant risk factors was performed using SAS 9.3 software. Results The rate of dyslipidemia was 31.6%. Multivariate logistic regression analysis showed that there were 20 or more cigarettes per day (OR = 1.293, 95% CI: 1.290-1.295), grade 3 alcohol consumption (OR = 1.103, 95% CI: 1.101-1.106), low level of physical activity (OR = 1.186, 95% CI: 1.185-1.188), high blood pressure (OR = 1.548, 95% CI: 1.546-1.550), hyperglycemia (OR = 1.589, 95% CI: 1.587-1.591) OR = 1.774, 95% CI: 1.772-1.777), obesity (OR = 2.565, 95% CI: 2.560-2.569, etc.) were all risk factors for dyslipidemia with statistical significance (P <0.01). Among them, obesity, central obesity and hyperglycemia are the most important risk factors. Conclusion Adult residents in Shandong Province have a high rate of dyslipidemia, and the prevalence of dyslipidemia should be lowered by changing diet and lifestyle as early as possible for high-risk groups with major risk factors for dyslipidemia.