论文部分内容阅读
目的:观察化纤汤辅助口服西药糖皮质激素泼尼松治疗特发性肺间质纤维化患者的临床疗效。方法:将56例特发性肺间质纤维化患者随机分为2组。治疗组28例,在口服糖皮质激素泼尼松的基础上加服中药化纤汤治疗;对照组28例,口服糖皮质激素泼尼松治疗。疗程为3月。观察2组患者临床症状的改善,肺总量(TLC)、一氧化碳弥散功能(DLco)的变化。结果:总有效率治疗组84.6%,对照组81.5%,2组比较,差异有显著性意义(P<0.05);治疗组咳嗽、气短喘息症状以及肺部velcro啰音的改善时间均较对照组缩短(P<0.05);治疗组较对照组TLC、DLco改善更加明显(P<0.05)。结论:中药化纤汤能显著改善特发性肺间质纤维化患者的临床症状和肺功能指标,疗效显著。
Objective: To observe the clinical efficacy of chemical fiber soup-assisted oral administration of western medicine glucocorticoid prednisone in patients with idiopathic pulmonary fibrosis. Methods: 56 patients with idiopathic pulmonary fibrosis were randomly divided into two groups. In the treatment group, 28 cases were treated with oral administration of glucocorticoid prednisone on the basis of traditional Chinese medicine and chemical fiber soup. The control group, 28 cases, were treated with oral glucocorticoid prednisone. Treatment for March. The clinical symptoms, lung volume (TLC) and changes of carbon monoxide dispersion function (DLco) were observed in two groups. Results: The total effective rate was 84.6% in the treatment group and 81.5% in the control group. There was significant difference between the two groups (P <0.05). The improvement time of cough, shortness of breath and wheezing in the treatment group and pulmonary velocro rales were all higher than those in the control group (P <0.05). The improvement of TLC and DLco in treatment group was more obvious than that in control group (P <0.05). Conclusion: Traditional Chinese Medicine Decoction can significantly improve the clinical symptoms and pulmonary function of patients with idiopathic pulmonary fibrosis, with significant curative effect.