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摘要目的抗肿瘤坏死因子疗法能有效治疗强直性脊柱炎(AS)常见的多发骨骼肌肉炎症。本研究运用全身MR成像(WBMRI)对接受依那西普治疗的AS病人的治疗反应进行评估,并与临床评估进行比较。方法 10例AS病人接受了12个月的依那西普治疗。病人在3个不同的时间点(0、26和52周)进行临床评估[Bath强直性脊柱炎病情活动指数(BASDAI)及C-反应蛋白(CRP)]和WBMRI检查(1.5 T,
Abstract Objective The anti-tumor necrosis factor (TNF) therapy is effective in treating multiple musculoskeletal inflammation that is common in ankylosing spondylitis (AS). This study evaluated the treatment response of patients undergoing etanercept in AS using whole-body MR imaging (WBMRI) and compared them with clinical assessment. Methods Ten patients with AS underwent 12-month etanercept treatment. The patients underwent clinical assessment [BASDAI and CRP] and WBMRI (1.5 T,