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目的观察异丙托溴铵与布地奈德雾化吸入治疗婴幼儿毛细支气管炎的临床疗效方法选择已经确诊患毛细支气管炎的婴幼儿患者148例,并随机分为两组,对照组74例,观察组74例。两组患者均进行吸氧、抗感染、化痰止咳平喘等综合治疗。对照组在综合治疗的基础上进行地塞米松静脉滴注,连续三天0.25～0.5mg/(kg·次);观察组在基础治疗的基础上进行布地奈德雾化剂0.5mg/(kg·次),异丙托溴铵1mg/(kg·次),3次/d,15min/次,采用空气压缩泵雾化。以一周为一个疗程,在一个疗程结束之后进行疗效评定。结果观察组在呼吸困难改善时间、喘憋消失时间、肺部体征消失时间以及住院天数方面均优于对照组,差异具有统计学意义(P<0.05)。结论异丙托溴铵与布地奈德雾化吸入用于治疗婴幼儿毛细支气管炎具有良好疗效。
Objective To observe the clinical efficacy of ipratropium bromide and budesonide inhalation in the treatment of bronchiolitis in infants and young children. Methods 148 cases of infantile infants who were diagnosed with bronchiolitis were selected and randomly divided into two groups, 74 cases in control group, Observation group of 74 cases. Two groups of patients were oxygen, anti-infection, Huatanzhike asthma and other comprehensive treatment. The control group received intravenous dexamethasone (0.25-0.5 mg / (kg · d)) on the basis of comprehensive treatment. On the basis of basic treatment, the observation group received budesonide nebulizer 0.5 mg / kg · Times), ipratropium bromide 1mg / (kg · times), 3 times / d, 15min / times, using air compression pump atomization. One week for a course of treatment, after a course of treatment efficacy evaluation. Results The observation group was better than the control group in improvement of breathlessness, disappearance of wheezing, disappearance of lung signs and days of hospitalization, the difference was statistically significant (P <0.05). Conclusion Ipratropium bromide and budesonide inhalation for the treatment of infantile bronchiolitis has a good effect.