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为探讨早产儿血浆总蛋白、肌酐和尿素氮变化与饮食及胃肠外营养支持的关系，对126例危重早产儿进行上述指标的动态监测。结果极低出生体重儿三项指标均值略低于非极低出生体重儿；混合营养组与葡萄糖营养组对比，后者血肌酐随禁食时间延长而逐渐降低，与前者相比有显著差别，血浆总蛋白和尿素氮两组差别不明显。说明在禁食早产儿中，血肌酐是监测营养状况指标之一。在肾功能正常情况下，若观察到血肌酐水平明显降低，应对其营养供给进行估价，保证所供给营养的质量。
To investigate the relationship between changes of plasma total protein, creatinine and urea nitrogen in preterm infants and diet and parenteral nutritional support, 126 critically ill preterm infants were monitored dynamically. Results The mean of three indicators of very low birth weight children was slightly lower than that of non-very low birth weight children. Compared with glucose nutrition group, the serum creatinine of the mixed nutrition group decreased gradually with the prolonged fasting time, which was significantly different from the former Plasma total protein and urea nitrogen difference between the two groups is not obvious. Description of fasting preterm children, serum creatinine is one of the indicators to monitor nutritional status. In the case of normal renal function, if the observed serum creatinine levels were significantly reduced, the nutritional supply should be evaluated to ensure the quality of nutrition provided.