目的：观察米非司酮配伍卡前列甲酯栓终止中期妊娠的临床效果。方法：对３１８例确诊为妊娠的妇女，妊娠天数≤１４４ｄ，口服米非司酮配伍阴道置卡前列甲酯栓，观察终止妊娠效果。结果：显示完全流产率９４３４％，不完全流产率５６６％，置卡前列甲酯栓后６ｈ内排出胎囊占９４０％。结论：反复间断应用卡前列甲酯栓宫缩作用增强，并未加重副反应 Objective: To observe the clinical effect of mifepristone combined with cardinal methylester suppository to terminate the second trimester pregnancy. Methods: 318 women diagnosed with pregnancy, gestational days ≤ 144d, oral administration of mifepristone vaginal card prepar methyl ester suppository, observe the effect of termination of pregnancy. Results: The rate of complete abortion was 9434% and incomplete abortion rate was 5.66%. The rate of fetal abortion was 940% within 6h after setting the card. Conclusion: Repeated intermittent card incision thiazole suppository enhanced, did not aggravate side effects