百草枯(Paraquat,PQ),化学名为1,1’-二甲基-4,4’-联吡啶阳离子盐,是一种有效且广泛使用的除草剂。一般成人PQ致死量为20%水溶液5~15ml,或口服致死剂量为30~50mg/kg。由于它毒性高、价格便宜、易于获得和缺乏有效的治疗手段,中毒后病死率达60%以上,已成为发展中国家中一个主要的公共卫生问题~([1])。进入体内的PQ有90%蓄积于肺内,远高于血浆和其他器官的浓 Paraquat (PQ), a chemical name of 1,1’-dimethyl-4,4’-bipyridinium cation salt, is an effective and widely used herbicide. The average adult lethal dose of PQ is 20% aqueous solution of 5 ~ 15ml, or oral lethal dose of 30 ~ 50mg / kg. Due to its high toxicity, its cheapness, its easy availability and its lack of effective treatment, the post-poison mortality rate has reached over 60% and has become a major public health issue in developing countries. [1] Into the body of PQ 90% accumulation in the lungs, much higher than the concentration of plasma and other organs