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血管内皮生长因子是一种分子量为34～45kD的同源二聚体碱性糖蛋白。它能特异性作用于血管内皮细胞,促进其有丝分裂、新生血管形成和增加血管通透性,在消化系肿瘤的生长、浸润和转移过程中发挥重要作用,本文就此作一综述。
Vascular endothelial growth factor is a homodimeric glycoprotein with a molecular mass of 34-45 kD. It can specifically act on vascular endothelial cells, promote its mitosis, neovascularization and increase vascular permeability, and play an important role in the growth, invasion and metastasis of digestive system tumors. This article reviews this issue.