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卵圆孔未闭与缺血性卒中和先兆性偏头痛相关,且可能为两者的发病原因。有几项研究表明经皮卵圆孔未闭封堵可能改善先兆性偏头痛的症状,但均存在不同的方法学问题。目前对于先兆性偏头痛患者仍推荐首选药物治疗,需要更多的前瞻性、随机、对照研究寻找卵圆孔未闭封堵治疗先兆性偏头痛的证据。
Patent foramen ovale is associated with ischemic stroke and migrainesia, and may be the causative agent of both. Several studies have shown that percutaneous patent foramen ovale closure may improve the symptoms of migraine aura, but there are different methodological problems. Currently, the preferred drug therapy is still recommended for migraine with aura, and more prospective, randomized, controlled studies are needed to find evidence of patent foramen ovale closure in the treatment of aura migraine.