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本研究对中国河北地区汉族183个健康无关个体进行12个STR基因座遗传多态性调查。采用QIAamp DNA midi试剂盒提取样本DNA,用Investigator HDplex试剂盒进行扩增及检测。结果在12个STR基因座共检测出167个等位基因和637种基因型,其分布符合Hardy-Weinberg平衡定律(P>0.05)。所调查的汉族人群12个STR基因座具有较好识别能力。
This study investigated the genetic polymorphism of 12 STR loci in 183 healthy unrelated individuals in the Han nationality of Hebei Province in China. The sample DNA was extracted using the QIAamp DNA midi kit and then amplified and detected using the Investigator HDplex kit. Results A total of 167 alleles and 637 genotypes were detected in 12 STR loci. The distribution was in accordance with Hardy-Weinberg equilibrium (P> 0.05). The 12 STR loci of Han population surveyed have better recognition ability.