我们收治了19例中、重度地方性克汀病,年龄为6—16岁,男14例,女5例,其中神经型18例,混合型1例。患者均有明显的智力低下和不同程度的听力障碍,3例达到白痴程度。患者傻相傻笑,表情淡漠,甚至对外界事物无反应,多数患者不认数,听不懂话,生活不能自理,身材矮小,体格发育落后,患者性腺和第二性征均低于同等年 We treated 19 cases of moderate and severe endemic cretinism, aged 6-16 years old, 14 males and 5 females, of which 18 cases of neurological, mixed in 1 case. Patients have significant mental retardation and varying degrees of hearing impairment, 3 patients reached the level of idiot. Patients silly smirk, apathetic expression, or even no reaction to the outside world, most patients do not recognize, do not understand the words, life can not take care of themselves, short stature, physical development, patients with gonads and secondary sexual characteristics were lower than the same year