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Gorham-Stout综合征(Gorham-Stout syndrome,GSS)是一种非常罕见和神秘的疾病,主要特征是大量骨头莫名其妙的被溶解或者消失.GSS明显不同于痛痛病和骨质疏松症.2001年,新疆自治区的一名8岁的小男孩被查出患有GSS,身体上的部分骨头已经被溶解.头发样品分析结果表明,患者头发中Cd,Cr,K,Na和Zn的含量与正常人迥异;Na和K的含量远远高于正常人,并且K/Na与正常人正好相反;有害元素Cd的含量是参考值的2倍多,而有益元素Cr和Zn却不足.4类比值研究表明,GSS患者的骨系统中微弱的成骨活动和强烈的破骨趋势并存.由此推断,微量元素的相互作用可能最终导致了怪病的发生.进一步调查显示,上述微量元素的失衡可以导致多种疾病,包括GSS和非典型性风湿性关节炎(atypical rheumatoid arthritis,ARA).流行病学调查表明,当地大约有四分之一的居民患有ARA.研究分析表明存在一种新的地球化学疾病.Gorham-Stout综合征、非典型性风湿性关节炎和腰椎间盘突出症之间存在相互联系.
Gorham-Stout syndrome (GSS) is a very rare and mysterious disease characterized by a large number of bones inexplicably dissolved or disappeared, and GSS is significantly different from that of pain and osteoporosis. , An 8-year-old boy from the Xinjiang Autonomous Region was found to have GSS and some of the body’s bones had been dissolved.The hair sample analysis showed that the content of Cd, Cr, K, Na and Zn in the hair of the patients was similar to that of the normal The content of Na and K is much higher than that of normal people, and K / Na is the opposite of normal people; the content of harmful element Cd is more than 2 times of the reference value, but the beneficial elements Cr and Zn are not enough.4 The study of analogy Suggesting that the weak osseointegration and strong osteoclastic tendencies in the skeletal system of patients with GSS coexist, suggesting that the interaction of trace elements may eventually lead to the development of strange diseases.Further investigation shows that the above imbalance of trace elements can lead to A variety of diseases, including GSS and atypical rheumatoid arthritis (ARA). Epidemiological surveys show that about a quarter of residents in the area have ARA. Research shows that there is a new type of earth Chemical diseases .Go There is an interplay between rham-stout syndrome, atypical rheumatoid arthritis and lumbar disc herniation.