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目的:研究药学服务对丙氨酰-谷氨酰胺(Ala-Gln)合理使用的干预效果。方法:查阅本院2013年5月248例使用过丙氨酰-谷氨酰胺的出院病历以获取基线数据,针对发现的问题实施一系列药学干预。2014年5月再次查阅228例使用过丙氨酰-谷氨酰胺的出院病历,比较和分析2组病历在药学干预前后丙氨酰-谷氨酰胺的使用差异。结果:实施药学干预后,选药适宜率(P<0.01)、稀释载体准确率(P<0.01)、氨基酸占比达标率(P<0.01)等评价指标均显著改善。结论:药学干预对丙氨酰-谷氨酰胺的合理使用产生显著的有益影响。
OBJECTIVE: To study the intervention effect of pharmacy service on the rational use of alanyl-glutamine (Ala-Gln). METHODS: We reviewed 248 hospitalized patients who had used alanyl-glutamine in May 2013 to obtain baseline data and conducted a series of pharmacological interventions on the identified problems. In May 2014, 228 cases of discharged alanine-glutamine were reviewed again. The differences of alanyl-glutamine before and after the intervention were compared and analyzed. Results: After the intervention, the appropriate drug selection rate (P <0.01), dilution carrier accuracy (P <0.01), and the proportion of amino acid to target ratio (P <0.01) were significantly improved. Conclusions: Pharmacological interventions have a significant beneficial effect on the rational use of alanyl-glutamine.