痛风是由于长期嘌呤代谢障碍、尿酸(嘌呤代谢的最终产物)生成过多或排出减少引起的尿酸堆积,堆积部位主要集中在软骨、软组织、肾脏及关节处。痛风的临床特点:(1)高尿酸血症;(2)特征性急性关节炎发作,严重者可导致关节活动障碍、畸形;(3)发作时疼痛难忍,是关节炎中疼痛最严重 Gout is due to long-term purine metabolic disorders, uric acid buildup caused by overproduction or depletion of uric acid (the final product of purine metabolism), with the accumulation sites predominantly concentrated in cartilage, soft tissue, kidneys and joints. The clinical features of gout: (1) hyperuricemia; (2) the onset of characteristic acute arthritis, severe cases can lead to joint movement disorders, deformities; (3) the onset of pain is unbearable, is the most severe pain in the arthritis