受载试剂用于有机合成反应近年来已有不少报道。Posner 用异丙醇/氧化铝作为 Meerwein-Pondorff-Verley 型的羰基还原剂,效果相当佳。然而 Posner 的特制脱水 W-200-N 氧化铝脱水时间太长(24小时),而且需要在充氮的手套箱中进行转移,操作较麻烦。我们改良了脱水氧化铝的制备方法,脱水时间显著缩短(6小时),而且受载试剂的转移及称量无需在 Loading reagents for organic synthesis reactions have been reported in recent years. Posner uses isopropanol / alumina as the Meerwein-Pondorff-Verley type carbonyl reductant and works well. However, Posner’s specially dewatered W-200-N alumina dehydrated for too long (24 hours) and required to be transferred in a nitrogen-filled glove box, which was cumbersome to operate. We have improved the preparation of dehydrated alumina, significantly shortened the dehydration time (6 hours), and no need to transfer and weigh the loaded reagents