我们前曾说明,刺激家兔腹部迷走神经外周端引起的降压反应由中枢和外周两方面因素造成,其中枢效应是通过内脏大神经中的传入纤维传入延脑所产生。刺激迷走神经外周端如何引起内脏大神经传入纤维兴奋?是否由于某些活性物质的释放刺激了胃肠壁内脏传入神经末稍引起?其中胃肠内含量丰富的组织胺和5-羟色胺是首先值得考虑的 We have previously shown that the antihypertensive response to stimulation of the peripheral vagus nerve in the rabbit abdomen results from both central and peripheral factors that are mediated by afferent fibers in the visceral large nerves that are introduced into the brain. Stimulate the peripheral vagus nerve how to cause the visceral nerve afferent fiber excitement? Whether the release of certain active substances to stimulate gastrointestinal wall visceral afferent nerve endings induced? Which rich in gastrointestinal tissue histamine and serotonin is the first worth considering