During the DY105-12, 14cruise (R/V DAYANG YIHAO, November 2003) on East Pacific Rise (EPR) 12- 13°N, the submarine hydrothermal activity was investigated and the CTD hydrocast was carried out at EPR12°39′N-12°54′N. From the temperature anomalies and the concentrations of magnesium, chlorine, bromine in seawater samples, we discover that magnesium depletes 9.3%-22.4%, chlorine and bro- mine enrich 10.3%-28.7% and 10.7%-29.0% respectively relative to normal seawater at the stations which have chemistry anomalies, moreover temperature and chemistry anomalies are at the same layer. The depletion of magnesium in the plume may be caused by a fluid lacking of magnesium which rises after the hydrothermal fluid reaches the equilibrium with ambient seawater, the enrichment of chlorine and bromine might be the result of inputting later brine which is generated by phase separation due to hydrothermal activity. In addition, the Br/Cl ratio in the abnormal layers at the survey area is identical to that in seawater, which implies that halite dissolution (or precipitation) occurs neither when the fluid is vented nor when hydrothermal fluid entraining ambient seawater rises to form plume. From the ab- normal instance at E55 station, it is very possible that there might exist a new hydrothermal vent site. During the DY105-12, 14 cruise (R / V DAYANG YIHAO, November 2003) on East Pacific Rise (EPR) 12-13 ° N, the submarine hydrothermal activity was investigated and the CTD hydrocast was carried out at EPR 12 ° 39’N- 12 ° 54’N. From the temperature anomalies and the concentrations of magnesium, chlorine, bromine in seawater samples, we discover that magnesium depletes 9.3% -22.4%, chlorine and bro- mine enrichments 10.3% -28.7% and 10.7% -29.0 % respectively relative to normal seawater at the stations which have chemistry anomalies, moreover temperature and chemistry anomalies are at the same layer. The depletion of magnesium in the plume may be caused by a fluid lacking of magnesium which rises after the hydrothermal fluid reaches the equilibrium with ambient seawater, the enrichment of chlorine and bromine might be the result of inputting later brine which is generated by phase separation due to hydrothermal activity. In addition, the Br / Cl ratio in the abnormal layers at the survey area is identic al to that in seawater, which implies that halite dissolution (or precipitation) occurs neither when the fluid is vented nor when hydrothermal fluid entraining ambient seawater rises to form plume. From the ab- normal instance at E55 station, it is very possible that there might exist a new hydrothermal vent site.