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b型流感杆菌(Hib)多糖-蛋白结合疫苗能有效控制侵袭性Hib病的流行。本文介绍了Hib结合疫苗的研制及应用情况,并对英国Hib结合疫苗免疫失败的原因进行了探讨。
The Hib polysaccharide-protein conjugate vaccine effectively controls the prevalence of invasive Hib disease. This article describes the development and application of Hib conjugate vaccine, and discusses the reasons for the failure of the UK Hib conjugate vaccine immunization.