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藻酸盐为铜绿假单胞菌生物膜的主要成分,为了探讨药物对铜绿假单胞菌产生藻酸盐的影响,对在含不同浓度红霉素和不同浓度头孢唑肟的普通琼脂培养基上生长的铜绿假单胞菌,采用高效液相色谱法测定其所产生的藻酸盐,结果红霉素对铜绿假单胞菌产生藻酸盐物质有抑制作用,而头孢唑肟则不能抑制藻酸盐的产生。说明红霉素对防治慢性铜绿假单胞菌感染症有意义。
Alginate is the main component of Pseudomonas aeruginosa biofilm. In order to investigate the effect of the drug on the alginate production by Pseudomonas aeruginosa, the effects of different concentrations of erythromycin and different concentrations of ceftizoxime on the common agar medium On the growth of Pseudomonas aeruginosa, using high performance liquid chromatography determination of the alginate produced, the results of erythromycin Pseudomonas aeruginosa alginate substances inhibited, while ceftizoxime can not be inhibited Alginate production. Description of erythromycin in the prevention and treatment of chronic Pseudomonas aeruginosa disease meaningful.