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近年来关于某些囊肿可以发生角化的问题已越来越引起重视。1956年Philipsen称此囊肿为牙原性角化囊肿。以后的一些研究根据角化囊肿具有复发倾向、侵犯性、可与基底细胞痣综合征并发及潜在肿瘤性质,认为应区别于其他囊肿,并应将牙原性囊肿重新分类。对于牙原性角化囊肿仍有各种不同认识。本文即主要讨论这些不同意见:病因病理、组织学表现、潜在肿瘤性质及临床行为。以后将发表第二部分,即组织学表现。
In recent years, the problem of keratosis of certain cysts has drawn more and more attention. In 1956 Philipsen called the cyst a keratin cyst. Some later studies based on keratosis cyst with recurrence tendency, invasive, with basal cell nevus syndrome and potential tumor nature, that should be distinguished from other cysts, and should be reclassified as dental cysts. There are still a variety of different understanding of dental keratocyst. This article focuses on these different opinions: etiology and pathology, histological manifestations, underlying tumor properties, and clinical behavior. The second part, the histological presentation, will be published later.