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近年来认为,青霉胺对慢性GVHD的皮肤改变有效。我们近来用青霉胺为主治疗2例慢性GVHD获较好疗效。现报告如下。 1 病例介绍例1,男,25岁。因发热、乏力、消瘦半月于1997年12月13日入院。经查血象、骨髓象确诊为急性粒细胞性白血病M2a型,予DA方案化疗一疗程后达完全缓解,之后予DA、IA及VA方案巩固化疗3个疗程。1998年4月20日行异基因外周血干细胞移植(Allo-PBSCT),1998年5月7日复查骨髓示造血重建。1998年6月6日耳后、腹部、背部均可见大片花斑样充血皮疹,伴皮肤搔痒。1998年6月16日
In recent years, penicillamine is believed to be effective in the skin changes of chronic GVHD. We recently used penicillin-based treatment of 2 cases of chronic GVHD better effect. The report is as follows. 1 case introduction example 1, male, 25 years old. Due to fever, fatigue, thin half-moon in December 13, 1997 admission. After investigation of blood, bone marrow confirmed as acute myeloid leukemia M2a type, to DA regimen after a course of treatment was completely relieved, after DA, IA and VA regimen to consolidate the three courses of chemotherapy. April 20, 1998 Allogeneic peripheral blood stem cell transplantation (Allo-PBSCT), May 7, 1998 review of bone marrow showed hematopoietic reconstructions. June 6, 1998 ears, abdomen, back are visible large spotted rash, with skin itching. June 16, 1998