当归水溶性提取物对5-FU诱导性贫血的改善作用

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探讨了当归提取物对5-氟尿嘧啶(5-FU)诱导性贫血模型小鼠的改善作用。方法:实验动物为8周龄雌性C5781/6小鼠,尾静脉注射5-FU 150 mg/kg,制作药物性贫血小鼠模型。从给予5-FU日开始经口给予当归提取物10d,对照组给予等量的生理盐水。给予5-FU后第5、10、15、20 d检测外周血红细胞数(RBC)、血红蛋白值 The effects of Angelica extract on 5-fluorouracil (5-FU)-induced anemia model mice were investigated. METHODS: The experimental animals were 8-week-old female C5781/6 mice. 5-FU 150 mg/kg was injected into the tail vein to produce an animal model of drug anemia. The angelica extract was orally administered 10 days from the day of administration of 5-FU, and the control group was given an equal amount of physiological saline. Detection of Peripheral Blood Red Blood Cell Number (RBC), Hemoglobin Value at 5th, 10th, 15th, and 20th Day after 5-Fu Administration
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