[目的]探讨认知行为疗法对膀胱肿瘤术后灌注化疗患者应对方式及遵医行为的影响.[方法]选择2015年3月至2017年9月本院收治的98例膀胱肿瘤术后灌注化疗患者为研究对象,随机分为对照组和观察组各49例.对照组给予包括健康教育、饮食干预、并发症预防在内的常规化疗护理干预,观察组联合应用认知行为干预.比较两组患者应对方式、遵医行为、不良反应等指标.[结果]观察组按时灌注化疗、遵医嘱服药、良好疾病认知、按时定期复查、无提前排药、生活习惯良好等评分明显高于对照组( P ＜0 .05) ;面对、乐观、寻求支持评分明显高于对照组,保守、逃避、自我依赖、情感宣泄、听天由命等评分明显低于对照组(P ＜0 .05) ;血尿、膀胱烧灼感、局部感染、消化系统不良反应以及膀胱刺激征等不良反应发生率明显低于对照组( P ＜0 .05) .[结论]认知行为疗法有助于促进膀胱肿瘤术后灌注化疗患者遵医行为养成,提升其积极应对行为能力,降低化疗相关不良反应发生率.“,”To explore the effect of cognitive behavioral therapy on coping style and compliance behavior of patients with bladder cancer after perfusion chemotherapy .[M ethods]From M arch 2015 to Sep‐tember 2017 ,98 patients with bladder cancer w ho received perfusion chemotherapy after operation were ran‐domly divided into control group and observation group ,49 cases in each group .T he control group was given routine chemotherapy nursing intervention including health education ,dietary intervention and prevention of complications ,w hile the observation group was given cognitive behavior intervention .T he coping style ,com‐pliance behavior and adverse reactions were compared between the two groups .[Results]In the observation group ,the scores of perfusion chemotherapy on time ,taking medicine according to doctor＇s advice ,good dis‐ease awareness ,regular review on time ,no early discharge of drugs and good living habits were significantly higher than those in the control group ( P ＜0 .05) ; the scores of calmness ,optimism and seeking support were significantly higher than those in the control group ,w hile the scores of conservatism ,evasion ,self‐reli‐ance ,emotional catharsis and resignation to fate were significantly higher than those in the control group ( P＜0 .05).T he incidence of adverse reactions such as hematuria ,bladder burning ,local infection ,adverse reac‐tion of digestive system and bladder irritation sign was significantly lower than that of the control group ( P ＜0 .05).[Conclusion]Cognitive‐behavioral therapy can help promote the compliance of doctors with bladder infu‐sion chemotherapy patients and improve the ability to actively respond to behaviors ,and reduce the incidence of chemotherapy‐related adverse reactions .