习惯性流产(HA)是指三次或更多次确定的连续自然流产,流产时妊娠<20周。临床妊娠中约有15％会流产,其中一半左右归因于非整倍体畸形和多倍体。已婚夫妇中约1％～2％有HA史,且在未分娩者再次妊娠50％会流产。因此,为深入研究并治疗HA,分析197对有HA史的夫妇(不包括非整倍体畸形者);均行遗传、内分泌、感染、解剖和自身 Habitual abortion (HA) refers to three or more consecutive spontaneous abortions defined as <20 weeks of pregnancy at abortion. Approximately 15% of clinical pregnancies will be aborted, with about half of them attributable to aneuploidy and polyploidy. About 1% to 2% of married couples have a history of HA, and 50% of those who have not yet delivered will have a miscarriage. Therefore, in order to further study and treat HA, 197 pairs of couples with HA history (excluding aneuploidy deformities) were analyzed; all had genetic, endocrine, infectious, anatomic and self