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目的 :观察正常眼后极部视网膜 (感光细胞 )功能。方法 :应用RETIscan多焦视觉电生理检查系统 (短M序列 )对2 4例 (32只眼 ) 10～ 30岁、4 0～ 6 0岁正常人眼后极部约 30°范围内视网膜行 6 1个刺激阵列的多焦视网膜电图 (multifocalelec troretinogram ,mfERG)一阶核反应 (firstorderkernel,FOK)测定 ,分别比较以黄斑中心凹为圆心排列的 1～ 5环FOKP1、N1波峰时和振幅密度值 ,以及黄斑鼻颞侧 ,后极部四个象限视网膜 ,后极部视网膜上、下半侧P1、N1波峰时和振幅密度值。结果 :随离心度增加 ,FOK反应P1、N1波有振幅密度值逐渐降低、峰时先逐渐缩短后逐渐延长的特征 ;10～ 30岁年龄组正常眼P1、N1波振幅密度值较 4 0～ 6 0岁年龄组大 ,峰时短 ,其差异有统计学意义 (P <0 0 5 ) ;各组的四个象限间和后极部视网膜上下半的P1波振幅密度值差异无统计学意义 (P >0 0 5 ) ;10～ 30岁年龄组正常眼黄斑鼻颞侧P1波振幅密度值鼻侧大于颞侧 ,其差异有统计学意义 (P <0 0 5 ) ,而 4 0～ 6 0岁年龄组黄斑鼻颞侧差异无统计学意义 (P >0 0 5 )。结论 :mfERG一阶核反应与视网膜感光细胞特别是视锥细胞的功能相对应。FOK振幅密度值随年龄增长而降低 ,说明视网膜感光细胞功能逐渐减退 ,FOK最短峰时的出现可能与有功能锥?
Objective: To observe the function of retina (photoreceptor cell) in the posterior pole of normal eyes. Methods: The RETIscan multifocal visual electrophysiological examination system (short M sequence) was used to evaluate the retinal function in 24 eyes (32 eyes), 10 to 30 years old, and 40 to 60 years old. The first orderkerker (FOK) assay of multifocalelec troretinogram (mfERG) was performed on a stimulus array. The first and fifth ring FOKP1, N1 peak and amplitude density were compared respectively. And the temporal and posterior pole quadrant of the macular nasal retina, the posterior pole of the retina, the lower half of P1, N1 peak time and amplitude density. Results: With the increase of the degree of centrifugation, the amplitude of P1 and N1 waves of FOK reaction decreased gradually, and then gradually shortened and gradually extended after the peak. The amplitude of P1 and N1 wave amplitude of normal eye in 10 ~ 30 age group was higher than that of 40 ~ There was a significant difference between the 60th and 60th years when the peak time was short (P <0 05). There was no significant difference in P1 wave amplitude density between the upper and lower retina of the four quadrants and the posterior pole in each group (P> 0.05). The amplitudes of P1 wave amplitudes on the temporal side of the normal ocular rhinoceros and nasalis in the 10-30 age group were higher on the nasal side than on the temporal side (P <0.05), while those on the 40th to the 6th There was no significant difference in temporal area of macular nasal in 0-year-old group (P> 0.05). Conclusion: The mfERG first order nuclear reaction corresponds to the function of retinal photoreceptor cells, especially cones. FOK amplitude density decreased with age, indicating that retinal photoreceptor cell function gradually diminished, the FOK shortest peak may occur with a functional cone?