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目的:检测并探讨晚期胃癌患者血清中C反应蛋白(CRP)水平对病情转归的评估价值。方法:收集2005-2014年住院治疗的40例晚期胃癌患者行化学治疗的临床资料,记录其临床转归情况,检测患者血清标本中的CRP水平,随访预后结果。结果:化学治疗有效者CRP较化学治疗前期明显下降。化学治疗无效者较化学治疗前升高,提示CRP水平与晚期胃癌患者预后相关。结论:血清中CRP水平可作为评估胃癌晚期转归的一项参考指标。
Objective: To evaluate and evaluate the serum C-reactive protein (CRP) levels in patients with advanced gastric cancer to assess the prognosis of the disease. Methods: The clinical data of 40 patients with advanced gastric cancer hospitalized from 2005 to 2014 in our hospital were collected. The clinical data of the patients were collected. The CRP level in the serum samples of patients and the outcome of follow-up were analyzed. Results: CRP in chemotherapy-effective patients was significantly lower than that in the pre-chemotherapy treatment. Chemotherapy ineffective than before chemotherapy increased, suggesting that the level of CRP in patients with advanced gastric cancer prognosis. Conclusion: Serum CRP levels can be used as a reference index for evaluating advanced gastric cancer outcome.