绪言关于急性高原适应不全症发病机制问题,近十多年来提出了不少假说。Haltgen等认为是动脉高压引起的。Genton等指出它与缺氧造成血栓有关。Hoon等发现缺氧使儿茶酚胺分泌过多。Hyers等提出它与肺泡与肺动脉血管之间氧梯度增加有关。Forbes,Hausen及Singh曾分别认为缺氧所造成的脑水肿是由于“钠泵”扰乱。中医根据辨证论治认为急性高原适应不全症的原因是肺脾“气虚”,用补肺脾为主的 Introduction On the issue of the pathogenesis of acute altitude sickness, many hypotheses have been put forward in the past decade. Haltgen think it is caused by arterial hypertension. Genton et al. Indicate that it is associated with hypoxia and thrombosis. Hoon found that hypoxia so that catecholamine secretion too much. Hyers et al. Suggest that it correlates with an increased oxygen gradient between the alveoli and pulmonary arteries. Forbes, Hausen, and Singh each thought that brain edema caused by hypoxia was disrupted by “sodium pump”. According to TCM diagnosis and treatment of acute altitude sickness due to inadequate lung and spleen “qi deficiency”, mainly with Bufei spleen