L783白血病小鼠脾细胞悬液接种SW1近交系小鼠腹腔后,可发展为全身性白血病。为了了解其发病过程,对接种后小鼠的血液学和病理学变化,作了动态观察。 材料和方法 一、材料 将L783白血病小鼠第48代的脾脏制成1∶3(W∶V)的生理盐水细胞悬液。取SW1近交系小鼠70只(雌雄各半,雌鼠体重为20～24克,雄鼠为22～26克),每鼠腹腔接种脾 Spleen cell suspension of L783 leukemia mice inoculated with SW1 inbred mice peritoneal cavity, can develop into systemic leukemia. In order to understand its pathogenesis, we made a dynamic observation of the hematological and pathological changes of mice after inoculation. Materials and Methods I. Materials The 48th generation spleens of L783 leukemia mice were made into a 1: 3 (W: V) physiological saline suspension. 70 SW1 inbred mice (half male and half female, 20-24 g body weight, male 22-26 g) were inoculated intraperitoneally