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目的探讨联合持续微量泵静脉用药在重度有机磷农药中毒抢救中的临床疗效。方法将北京急救中心2001-2004年所救治的52例重度有机磷农药中毒患者分为治疗组和对照组,治疗组采用阿托品与碘解磷定先静脉注射后持续微量泵静脉维持给药方法,对照组采用传统间歇给药方法。两组均经过洗胃、补液及对症处理。结果治疗组痊愈26例,死亡1例(3.7%),无反跳病例;对照组痊愈18例,死亡7例(28%),反跳6例(24%),治疗组病死率、反跳发生率较对照组显著降低(P<0.05)。而两组阿托品化时间、阿托品总量及治疗天数均无显著性差异(P﹥0.05)。结论联合持续的微量泵静脉给药在抢救重度有机磷中毒中方法简单、可靠,治疗效果显著。
Objective To investigate the clinical efficacy of combined continuous micropump intravenous therapy in the rescue of severe organophosphorus pesticide poisoning. Methods Fifty-two patients with severe organophosphorus pesticide poisoning treated by Beijing Emergency Center from 2001 to 2004 were divided into treatment group and control group. The treatment group was treated with continuous intravenous injection of atropine and iodine- Control group using the traditional intermittent drug delivery method. After two groups have gastric lavage, fluid replacement and symptomatic treatment. Results In the treatment group, 26 cases were cured and 1 case (3.7%) died without rebound. In the control group, 18 cases were cured, 7 cases died (28%), 6 cases rebounded (24%). The mortality and rebound The incidence was significantly lower than that of the control group (P <0.05). The two groups of atropisol time, the total amount of atropine and treatment days were no significant difference (P> 0.05). Conclusion Combined continuous micropump intravenous injection in the rescue of severe organophosphorus poisoning in the method is simple and reliable, the treatment effect is remarkable.