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目的 了解贵州省黔南地区农村少数民族居民高尿酸血症患病现状及其危险因素,为采取相应的干预措施提供参考依据.方法 于2015年1月-2016年12月采用整群随机抽样方法在贵州省黔南地区抽取143 687名≥18岁农村常住少数民族居民进行问卷调查、体格检查和实验室检测.结果 贵州省黔南地区143 687名常住农村少数民族居民中,患高尿酸血症者26 341例,患病率为18.33％,标化患病率为18.21％;多因素非条件logistic回归分析结果显示,年龄30～59岁、家庭年人均收入＞3 000元、高甘油三酯(TG)、高总胆固醇(TC)、高血压、超重/肥胖、吸烟、经常吃肉/鱼/虾/蛋、经常吃动物内脏和居住地海拔高度≥2 000m是贵州省黔南地区农村少数民族居民高尿酸血症患病的危险因素.结论 贵州省黔南地区农村少数民族居民高尿酸血症患病率较高,应针对该地区少数民族居民高尿酸血症患病的危险因素进行干预.“,”Objective To examine the prevalence and risk factors of hyperuricemia (HUA) among minority rural residents living in southern regions of Guizhou province and to provide references for implementing relevant interventions.Methods A total of 143 687 minority permanent rural residents (≥ 18 years old) were randomly selected in Qiannan Buyi and Miao Autonomous Prefecture (Qiannan) of Guizhou province using cluster random sampling and surveyed with a face-to-face interview,physical examination,and laboratory test between January 2015 and December 2016.Results Among the participants,a total of 26 341 HUA cases were diagnosed;the prevalence rate and standardized prevalence rate of HUA were 18.33 ％ and 18.21％.The results of multivariate logistic regression analysis revealed that aged 30-59 years,with a household annual per capita income ＞ 3 000 RMB yuan,hypertriglyceridemia,hypercholesterolemia,hypertension,overweight or obesity,smoking,frequent intake of meat/fish/shrimp/egg,frequent intake of offal,and residing in a high altitude (≥ 2 000 meters) region were risk factors of hyperuricemia for the participants.Conclusion The prevalence of hyperuricemia is relatively high among adult minority rural residents in Qiannan area of Guizhou province and targeted interventions on risk factors of hyperuricemia should be implemented in the population.