原发性肾病综合征是以大量蛋白尿、明显低蛋白血症、高脂血症和较明显水肿为特征的一组原发性肾小球疾病。在其发病机制中,补体系统不仅参与特异性免疫应答,也参与特异性防御反应。为此,本文拟探讨参与补体激活的旁路(替代)途径的重要分子补体C3和B因子在原发性肾病综合征... Primary nephrotic syndrome is a group of primary glomerular diseases characterized by massive proteinuria, marked hypoalbuminemia, hyperlipidemia and more pronounced edema. In its pathogenesis, the complement system not only participates in the specific immune response, but also participates in the specific defense response. To this end, we intend to investigate the important molecular complement C3 and factor B involved in complement activation by the alternative (alternative) pathway in primary nephrotic syndrome.