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目的观察舒芬太尼和罗哌卡因在腰硬联合阻滞分娩镇痛的临床应用效果。方法选择初产妇50例,随机分为A、B两组,每组25例。两组分别在蛛网膜下腔注射舒芬太尼5μg和罗哌卡因3mg,待产妇VAS≥3分时启用自控PCA泵维持镇痛。并对两组的不同时间点进行VAS评分,记录镇痛维持时间、不良反应及运动阻滞情况等指标。结果A组镇痛起效时间、镇痛效果、镇痛维持时间均明显优于B组(P<0.05或0.01),并且对产程、新生儿Apgar评分的影响较小。结论舒芬太尼行腰硬联合阻滞分娩镇痛能提供良好的镇痛效果,具有起效快、镇痛强、持续时间长、副作用少等优点。
Objective To observe the clinical effect of sufentanil and ropivacaine on analgesia induced by combined spinal and epidural block. Methods Fifty primiparae were randomly divided into A and B groups, with 25 cases in each group. Two groups were injected subarachnoid sufentanil 5μg and ropivacaine 3mg, to be maternal VAS ≥ 3 minutes to enable controlled PCA pump to maintain analgesia. The VAS scores were recorded at different time points in two groups. The duration of analgesia, adverse reactions and motor block were recorded. Results The onset time of analgesia, the analgesic effect and the duration of analgesia in group A were significantly better than those in group B (P <0.05 or 0.01), and had little effect on the Apgar score of labor and neonates. Conclusion sufentanil combined spinal and epidural block analgesia can provide good analgesic effect, with rapid onset, strong analgesic, long duration, fewer side effects.