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莫西沙星(moxifloxacin)是新一代喹诺酮类抗菌药,对G~+、G~-、厌氧菌和非特异性病原菌有效,目前已广泛应用于临床治疗社区获得性肺炎、慢性支气管炎急性发作、呼吸道感染、急性鼻窦炎等。据报道莫西沙星ADR发生率为11.44%,通常表现为皮疹、皮肤瘙痒、恶心、呕吐、肝功能异常、头晕、头痛等症状。现将我院近2年来发生的5例静脉滴注莫西沙星致肝功能异常的病例报道如下。
Moxifloxacin, a new generation of quinolone antibacterials, is effective against G ~ +, G ~ -, anaerobic bacteria and non-specific pathogens. It has been widely used in clinical treatment of community-acquired pneumonia, acute exacerbation of chronic bronchitis, Respiratory infections, acute sinusitis. The incidence of ADR in moxifloxacin is reported to be 11.44%, usually as rash, pruritus, nausea, vomiting, abnormal liver function, dizziness, headache and other symptoms. Now in our hospital in the past 2 years occurred in 5 cases of intravenous drip Moxifloxacin liver dysfunction cases are reported below.