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目的探讨甲状腺激素水平的变化对急性心肌梗死 (AMI)的严重度和预后的临床价值。方法对 5 6例 AMI患者检测了甲状腺素的变化及心肌酶的测定 ,其中对 2 9例进行动态检测。结果 AMI患者的 T3、T4、FT3、FT4明显低于正常 (P<0 .0 1) ,梗死面积越大 ,病情危重患者甲状腺激素变化越明显 ,其心肌酶谱越高 ,T3、FT3下降越明显 ,低 T3、T4、FT3、FT4、TSH病死率明显高于正常 T3、T4、FT3、FT4、TSH。结论检测甲状腺激素水平的变化有助于判断心肌梗死面积的大小、程度轻重 ,对心肌梗死的预后判断有着实际的临床价值 ,可以互补心肌酶测定的不足
Objective To investigate the clinical value of the changes of thyroid hormones on the severity and prognosis of acute myocardial infarction (AMI). Methods Twenty-six AMI patients were tested for the change of thyroxine and the determination of myocardial enzymes, of which 29 cases were dynamically detected. Results The levels of T3, T4, FT3 and FT4 in patients with AMI were significantly lower than those in patients with normal AMI (P <0.01). The larger the infarct size was, the more obvious the change of thyroid hormone was. Obviously, low T3, T4, FT3, FT4, TSH mortality was significantly higher than normal T3, T4, FT3, FT4, TSH. Conclusion The detection of thyroid hormone levels will help determine the size of myocardial infarction, the degree of severity, the prognosis of myocardial infarction have a real clinical value, can complement the lack of myocardial enzyme determination