川崎综合征(KS)是一种以全身小血管炎为主要病理改变的小儿急性发热性疾病。本病虽呈自限性,但有15～24%的病儿可伴发冠状动脉损害,如冠状动脉瘤、动脉扩张或狭窄,部分病儿导致冠状动脉局部出血、心肌梗塞甚至猝死。在美国和日本本病已被认为是取代风湿热成为小儿后天性心脏病的主要病因之一。KS的病因目前仍不清楚,从病人的发病呈一 Kawasaki syndrome (KS) is a small acute vasculitis systemic pathological changes in children with acute febrile disease. Although the disease was self-limiting, but 15 to 24% of sick children may be associated with coronary artery lesions, such as coronary aneurysms, arterial dilation or stenosis, some sick children lead to coronary local bleeding, myocardial infarction or even sudden death. In the United States and Japan, the disease has been considered as a replacement for rheumatic fever as one of the major causes of acquired heart disease in children. The etiology of KS is still unclear, from the onset of the patient was one