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恶性淋巴网状细胞病(简称恶网病)仅以肝病为临床表现者罕见。作者报道4例由淋巴网状细胞浸润引起的暴发型肝病.4例患者临床特征非常相似:皆有发热和乏刀,恶心,呕吐及进行性黄疸.死前合并症有肾衰,凝血异常和败血症。实验室特征:SGOT,Akp,Bil 皆升高;3例有白细胞减少和LDH 明显增高.这些均为原发性肝病的特征。因此,分别诊断为:暴发型病毒性肝炎(例1.4).酒精性肝炎(例2)和药物性肝炎(安氟醚)(例3).仅1例尸检前作出恶性病诊断、4例皆于数周内死于肝衰竭.4例尸检,表现为肝、脾、淋巴结和骨髓等多器官受累.
Malignant lymphatic reticular cell disease (referred to as evil net disease) only liver disease as a clinical manifestation of rare. The authors report four cases of fulminant liver disease caused by lymphoreticular infiltration, and the clinical features of the four patients were very similar: fever and lack of knives, nausea, vomiting and progressive jaundice. Premenstrual complications were renal failure, coagulation abnormalities, septicemia. Laboratory characteristics: SGOT, Akp, Bil are elevated; 3 cases of leukopenia and LDH was significantly increased These are the characteristics of primary liver disease. Therefore, they were diagnosed as fulminant hepatitis (case 1.4), alcoholic hepatitis (case 2), and drug-induced hepatitis (enflurane) (case 3) .Among 1 case of an autopsy, Died of liver failure in a few weeks, 4 cases of autopsy, manifested as liver, spleen, lymph nodes and bone marrow and other organs involved.