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【目的】观察地佐辛对妇科腹腔镜手术患者术后疼痛的影响。【方法】选取2012年1月至2014年1月在本院进行腹腔镜下妇科手术的患者108例，采用随机数表法将其分为观察组和对照组，每组54例。观察组：术毕前30～40 min 对其静脉注射0．1 mg／kg 的地佐辛（生理盐水稀释至10 mL）；对照组：术毕前30～40 min 对其静脉注射同容量的生理盐水。对比两组患者术后不同时间点的视觉模拟评分（VAS）、舒适度（BCS 评分）、镇静效果（Ramsay 评分）、术后不良反应发生情况。【结果】观察组患者术后不同时间点的镇痛和镇静效果及舒适度评分显著优于对照组患者，比较两组间差异具有统计学意义（ P ＜0．05）。观察组患者术后的不良反应发生率显著低于对照组患者，比较两组间差异具有统计学意义（ P ＜0．05）。 【结论】术前使用地佐辛能够有效缓解妇科腹腔镜手术患者术后24 h 内患者的疼痛，具有较好的镇痛和镇静效果，能增加患者术后的舒适度，有效降低术后不良反应的发生率，可在临床上进一步推广应用。“,”Objective] To explore the effect of dezocine on postoperative pain in laparoscopic patients .[Methods] From January 2012 to January 2014 ,a total of 108 patients undergoing laparoscopic hysterectomy were randomly divided into observation and control groups ( n = 54 each) .At 30 ~ 40 min pre‐surgery ,an in‐travenous injection of 0 .1 mg/kg dezocine (diluted with saline to 10 ml) was administered for observation group while the same volume of saline for control group .At different timepoints ,visual analog scale (VAS) , comfort level (BCS score) ,sedation status (Ramsay score) and postoperative adverse events .[Results] At different timepoints ,the analgesia and comfort scores of observation group were significantly better than those of control group .And the inter‐group differences were statistically significant ( P < 0 .05) .And the postoper‐ative incidence of adverse reactions was significantly lower in observation group than that in control group . And the inter‐group differences were statistically significant ( P < 0 .05) .[Conclusion] For mini‐invasive total uterus removal ,preoperative use of dezocine may effectively relieve 24h postoperative pain better analgesic and sedative effects ,boost patient comfort and reduce the postoperative incidence of adverse reactions .Such a practice is worth wider popularization .