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地中海贫血是我国南方最常见的遗传性血液病,广东省人群中的基因携带率为4.11%,仅次于广西(14.59%)居全国第二,由于目前对该病尚无根治办法,通过产前诊断和选择性流产淘汰重症患儿是唯一有效的优生措施。在筛查工作中,主要是检测出携带者,本文提出利用血常规检验方法,观察“平均红细胞体积(MCV)值,作为一种筛选人群的尝试。我院以MCV作为地贫筛查手段对2年来1800例孕妇作检测,取得满意效果,现报告如下。
Thalassemia is the most common hereditary hematological disease in South China. The population carrying rate of gene in Guangdong Province was 4.11%, second only to Guangxi (14.59%), ranking the second in the country. Because there is no cure for the disease at present, Pre-diagnosis and selective abortion of critically ill children is the only effective eugenic measures. In the screening work, mainly to detect carriers, the paper proposed the use of blood test methods, the observation of the average volume of red blood cells (MCV) value, as an attempt to screen the crowd in our hospital MCV as thalassemia screening means 1800 cases of pregnant women in 2 years for testing, and achieved satisfactory results, are as follows.