围生期缺氧缺血性脑损伤(hypoxia-ischemiabrain damage,HIBD)是导致脑瘫和其他神经系统慢性致残性疾病的主要原因。统计结果显示,足月新生儿全身窒息的发生率为2‰~4‰,低体重儿(出生体重2500g)窒息的发生率约为60%。所有患缺氧缺血性脑病的窒息患儿中,20%~50%在新生儿期即死 Perinatal hypoxic-ischemic brain injury (HIBD) is the leading cause of cerebral palsy and other chronic disabling diseases of the nervous system. Statistics show that the incidence of systemic suffocation of full-term newborns was 2 ‰ ~ 4 ‰, and the incidence of asphyxia in low birth weight children (birth weight 2500g) was about 60%. Of all children with asphyxia with hypoxic-ischemic encephalopathy, 20% to 50% die in the neonatal period