为了研究微量元素与碘缺乏病及氟中毒的关系 ,1996年 7月在陕西省蒲城县钤铒乡城南村和龙阳乡三家村调查了儿童氟斑牙和儿童甲状腺肿大的患病情况 ,测定了水、土壤、尿液中的微量元素。结果表明 ,城南村儿童氟斑牙患病率为 31.3% ,三家村为 97.2 % ,两村差异有高度显著性 (P<0 .0 1) ;儿童甲状腺肿大率城南村和三家村分别为 13.6 %和2 0 .0 % ,差异无显著性 (P>0 .10 )。城南村水氟含量为 0 .96 mg/ L,水碘含量为 8.6 6 μg/ L,土壤水溶性氟含量 5 .38mg/ kg,土壤水溶性碘含量为 34 .0 6 μg/ kg,尿氟含量为 1.92 mg/ L,尿碘含量为 138.45 μg/ L;而三家村水氟含量为 4.46 mg/ L,水碘含量为 174.4μg/ L,土壤水溶性氟含量 10 .13mg/ kg,土壤水溶性碘含量为 95 .33μg/ kg,尿氟含量为 14.97mg/ L,尿碘含量为 1142 .11μg/ L。据此认为 ,三家村环境氟含量过高引起氟中毒流行 ,而过量摄入碘引起高碘性甲状腺肿 In order to study the relationship between trace elements and iodine deficiency disorders and fluorosis, the prevalence of goiter in children and children in July 1996 was investigated in Chengnan Village, Qiongba Township, Pucheng County, Shaanxi Province and Sanjia Village, Longyang Township , Measured in water, soil, urine trace elements. The results showed that the prevalence rate of dental fluorosis was 31.3% in Chengnan village and 97.2% in Sanjia village, the difference between the two villages was highly significant (P <0.01). The rates of goiter and Sanjia village in children in Chengnan were 13.6% and 20.0%, the difference was not significant (P> 0 .10). The water content of Chengnan Village was 0.96 mg / L, the water iodine content was 8.66 μg / L, the soil water-soluble fluorine content was 5.38 mg / kg, the soil water-soluble iodine content was 34.06 μg / kg, While the content of iodine in urine was 138.45 μg / L in Sanjiancun, while the water content in Sanjia village was 4.46 mg / L, the water iodine content was 174.4 μg / L, the soil water-soluble fluoride content was 10.13 mg / kg, The iodine content was 95.33μg / kg, the urinary fluoride content was 14.97mg / L, the urinary iodine content was 1142.11μg / L. Therefore, the high fluoride content in Sanjiaocun environmental fluorosis caused by epidemic, and excessive intake of iodine caused by high iodine goiter