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目的:探讨全程神经内镜下经颞下锁孔Kawase入路切除三叉神经鞘瘤的临床疗效。方法:复旦大学附属中山医院神经外科自2018年9月至2019年6月采用神经内镜下经颞下锁孔Kawase入路切除三叉神经鞘瘤患者4例，现回顾性分析患者的临床资料、疗效和安全性。结果:4例患者的肿瘤均完全切除，无死亡病例。1例患者术后左侧咬合力弱和面部麻木，经治疗和随访后无明显改善；1例患者术后左侧面部麻木和左侧肢体肌力下降，经治疗和随访后明显改善；余2例患者术后无并发症。患者随访4~13个月，均正常生活，未见肿瘤复发。结论:神经内镜下经颞下锁孔Kawase入路具有微创、路径短、暴露范围广、视野清晰等优点，可以安全有效地切除三叉神经鞘瘤。“,”Objective:To investigate the clinical experience of neuroendoscopic subtemporal keyhole Kawase approach for trigeminal neurinoma resection.Methods:A retrospective study of general clinical data, postoperative effect and safety was performed in 4 patients with trigeminal neurinoma who underwent resection via neuroendoscopic keyhole Kawase approach in our hospital from September 2018 to June 2019.Results:Total resection was achieved in 4 patients, and there was no death. Two patients suffered from mild postoperative trigeminalnerve dysfunction: one had weak left bite force and facial numbness after surgery, which were not obviously improved after treatment and follow-up; one had left facial numbness and decreased left limb muscle strength after surgery, which were obviously improved after treatment and follow-up. Postoperative complications were not found in the other two patients. Follow-up for 4-13 months showed that all patients had a normal life without tumor recurrence.Conclusion:The approach has obvious advantages, such as minimal invasion, short path, wide exposure range and clear vision, which can help to safely and effectively remove trigeminal neurinoma.