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目的:探讨直肠癌术后预防腹腔转移及肝转移的方法。方法:把66例直肠癌切除术后病人分成两组,腹腔温热灌洗及术后动脉灌注化疗组35例为治疗组,单纯静脉化疗组31例为对照组。对其腹腔转移率、肝转移率及5年中位生存率进行比较。结果:治疗组腹腔转移率19.8%,肝脏转移11.9%,5年中位生存率64.6%。对照组腹腔转移率44.3%,肝脏转移率29.8%,5年中位生存率39.6%。结论:术中腹腔温热灌洗化疗及术后动脉灌注化疗对直肠癌术后腹腔转移及肝脏转移有良好的防治作用。
Objective: To explore the method of prevention of peritoneal metastasis and liver metastasis after rectal cancer surgery. Methods: Sixty-six patients with rectal cancer after resection were divided into two groups: 35 patients in the group treated with intraperitoneal warm lavage and postoperative arterial infusion chemotherapy, and 31 patients in the simple intravenous chemotherapy group as control group. The peritoneal metastasis rate, liver metastasis rate and 5-year median survival rate were compared. Results: In the treatment group, the rate of peritoneal metastasis was 19.8%, the liver metastasis was 11.9%, and the median 5-year survival rate was 64.6%. In the control group, the rate of peritoneal metastasis was 44.3%, the rate of liver metastasis was 29.8%, and the median 5-year survival rate was 39.6%. CONCLUSION: Intraperitoneal hyperthermic perfusion chemotherapy and postoperative arterial infusion chemotherapy have a good preventive and therapeutic effect on peritoneal metastasis and liver metastasis of rectal cancer after operation.