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目的:探讨依达拉奉联合高压氧治疗一氧化碳中毒后迟发性脑病的临床疗效。方法:选择广州市番禺中心医院2014年6月至2015年7月收治的一氧化碳中毒患者64例,按照患者的入院就诊时间将其平均分为对照组和观察组,每组32例。观察组采用依达拉奉联合高压氧治疗,对照组接受常规治疗,最后将两组一氧化碳中毒患者的治疗效果进行对比和统计。结果:经不同方法治疗后,观察组的治疗总有效率高于对照组,不良反应发生率低于对照组,总体健康评分也明显高于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:在一氧化碳中毒治疗中应用依达拉奉联合高压氧治疗,效果显著,同时具有较高的安全性。
Objective: To investigate the clinical efficacy of edaravone and hyperbaric oxygen in the treatment of delayed encephalopathy after carbon monoxide poisoning. Methods: Sixty-four patients with carbon monoxide poisoning admitted to Panyu Central Hospital of Guangzhou City from June 2014 to July 2015 were divided into control group and observation group according to the time of admission. The patients in each group had 32 cases. The observation group was treated with edaravone combined with hyperbaric oxygen and the control group received routine treatment. Finally, the treatment effect of two groups of patients with carbon monoxide poisoning was compared and statistically analyzed. Results: After treatment by different methods, the total effective rate of observation group was higher than that of control group, the incidence of adverse reactions was lower than that of control group, and the overall health score was also significantly higher than that of control group. The differences were statistically significant (P <0.05). Conclusion: The application of edaravone combined with hyperbaric oxygen therapy in the treatment of carbon monoxide poisoning has obvious effect and high safety.