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目的了解2010—2011年广州市不同时段人群甲型H1N1流感(甲流)的感染水平,为完善防控措施提供依据。方法采用多阶段随机抽样方法,以广州市未接种甲流疫苗人群为对象,开展3次个案调查,并采集血液样本,采用血凝抑制试验(HI)进行抗体检测,抗体滴度≥1∶40判为阳性。结果共调查3 865人,检测甲流抗体阳性804人,阳性率20.8%;2010年1月、3月和2011年8月抗体阳性率分别为22.7%、14.2%、25.5%;3次调查抗体阳性率最高为16～24岁组;学生的阳性率较高。结论广州健康人群H1N1免疫屏障尚未建立,需加强流感防控宣传和疫苗接种。
Objective To understand the infection level of Influenza A (H1N1) in different periods of Guangzhou from 2010 to 2011, so as to provide basis for improving prevention and control measures. Methods A multi-stage random sampling method was used to investigate the case-control study in Guangzhou City. The blood samples were collected and tested for HI by HI. The antibody titers ≥1:40 Convicted to be positive. Results A total of 3 865 people were tested, of which 804 were positive for influenza A antibody. The positive rate was 20.8%. The positive rates of antibodies in 22 cases were 22.7%, 14.2% and 25.5% respectively in January, March and August in 2011. The highest positive rate of 16 to 24 years old group; the higher the positive rate of students. Conclusion The immunization barrier of H1N1 in healthy population of Guangzhou has not been established yet, so influenza prevention and control publicity and vaccination should be strengthened.