2011年11月23日美国食品药品管理局(FDA)批准酒石酸唑吡坦舌下片(商品名Intermezzo)用于治疗半夜醒后难以再入眠的失眠病征。该药是FDA批准的首个用于治疗此种适应症的药物。Intermezzo仅应用于半夜醒后至少还有4h睡眠时间的人群。一旦饮酒或使用其他辅助睡眠药物,不应服用该药。 November 23, 2011 The U.S. Food and Drug Administration (FDA) approved the use of zolpidem tartrate sublingual tablets (Intermezzo) for the treatment of insomnia that is refractory to further sleep after midnight. This drug is the first FDA-approved drug to treat this condition. Intermezzo applies only to people who sleep for at least 4 hours after midnight. The drug should not be taken when drinking or using other sleep-deprived drugs.